A comprehensive examination of mandatory gender quotas for corporate boards reveals the complexities surrounding the promotion of gender equality in leadership positions. The urgency for increased representation of women in boardrooms is underscored by the pervasive issue of gender discrimination against women in leadership roles across various sectors. Based on the Institutional theory, this study aimed to analyse the implications of implementing gender quotas through a systematic literature review, which identified 126 relevant studies for final consideration. The findings categorised the arguments for gender quotas into three main frameworks: democratic, deontological, and business case. While supporters argue that these quotas effectively improve talent distribution in the workforce, critics assert that such measures undermine the principles of meritocracy. However, the findings emphasised that it is crucial to cultivate an environment that acknowledges and champions women's leadership potential, thereby fostering a more inclusive and equitable landscape in public management. Furthermore, it is recommended that governments provide transparency regarding companies that achieve their gender representation targets, thereby fostering a peer-pressure dynamic to ensure compliance.

Objective: We aimed to explore the effect of the mixed decoction of Inula cappa and Serissa japonica (IS) on carbon tetrachloride (CCl4)-induced acute liver injury. Methods: Sixty mice were randomly divided into control group, model group, bifendate group (0.2 g/kg) and IS (2, 1and 0.5 g/kg) groups. Mice in each group were received intragastric administration for 7 days. Two hours after the last administration, except the control group, the mice in the other groups were intraperitoneally injected with 40% CCl4 peanut oil solution (10 ml/kg) to establish the acute liver injury model. After 24 h of fasting, serum and liver tissues were collected. The pathological changes of liver were observed by HE staining. The liver index of mice was detected by weighing method. The content of ALT and AST in serum, the activity of SOD and the content of MDA in liver tissues were detected by ELISA. \nResults: Compared with the model group, the necrosis degree and scope, and the structural damage of hepatocyte were significantly ameliorated in the bifendate, high-dose IS and medium-dose IS groups. Compared with the model group, IS and bifendate could significantly inhibit the liver index, serum AST and ALT levels and the content of MDA in the liver of mice with acute liver injury, and improve the activity of SOD (P < 0.05). Compared with the treatment effect of bifendate, the hepatoprotective effect of high-dose IS was significant (P < 0.05). \nConclusion: The mixed decoction of Inula cappa and Serissa japonica has a protective effect on acute liver injury.

Purpose: Long non-coding RNA (lncRNA) small nucleolar RNA host gene 17 (lncRNA SNHG17) is dysregulated in many types of human tumors and acts as a tumor suppressor or promoter according to the tumor type. However, the role of lncRNA SNHG17 in hepatocellular carcinoma (HCC) has been uninvestigated. \nMethods: Counting on qRT-PCR assay, lncRNA SNHG17 expression in HCC tissues and cell lines (PLC, Hep3B, Huh7 and 7721) was investigated. By utilizing CCK-8 and flow cytometry assays, cell viability and cell cycle were evaluated. qRT-PCR and western blot was implemented to examine p15, p16, p21, p27 and p57 expression levels in HCC cells. \nResults: We firstly found that expression levels of lncRNA SNHG17 in HCC tissues and cell lines was higher than that in para-carcinoma tissues and QSG-7701 cells (P <0.05). In addition, we observed that patients with tumor size ≥ 5cm, HCC stages III-IV or poor pathological histological types, lncRNA SNHG17 expression were significantly higher than those with tumor size < 5 cm, HCC stages I-II or good histopathological types (P <0.05 ). In vitro studies showcased that low expression of lncRNA SNHG17 restrained HCC cell proliferation and evoked cell cycle arrest. Further, silence of lncRNA SNHG17 up-regulated p57 expression in HCC cells. \nConclusions: Our research shows that lncRNA SNHG17 plays a tumor promoter in HCC, which may provide new clues for the treatment of HCC.

To differentiate the 5 types of pediatric sepsis by integrating the mRNA data and PINs analysis. Explore the potential genes related to pediatric sepsis through different methods to prevent and treat pediatric sepsis. 129 pediatric sepsis were enrolled including 23 SIRS, 24 uncomplicated sepsis, 21 severe sepsis, 33 septic shock and 28 sepsis death. Differentiation module of SIRS, uncomplicated sepsis, severe sepsis, septic shock and sepsis death were 3, 3, 1, 0 and 0, respectively. The nodes of SIRS modules are 8, 7 and 4, respectively. Corresponding edges are 28, 21 and 6, respectively. The nodes of uncomplicated sepsis are 6, 3 and 5, respectively and corresponding edges are 15, 3 and 10. The nodes of severe sepsis module are 3 and corresponding edges are 3. One differentiation module of sepsis death containing 4 nodes and 6 edges is obtained. The genes participate in ribosome and cell cycle pathways probably play important roles in development of pediatric sepsis.

Background: To evaluate the influence of effective enteral nutrition support on delirium in ICU patients with mechanical ventilation.\nMethods: 51 patients were divided into observation group and control group according to the nutrition support. Patients in the observation group received enteral nutritional support within 48h after mechanical ventilation, while patients in the control group received parenteral nutrition support within 48 hours after mechanical ventilation, and then enteral nutrition support after 48 hours. The mechanical ventilation time, duration of delirium, ICU length of hospital stay, lymphocyte number before and after the intervention, body weight, complications, and nutritional intervention time and nutritional standard time of patients in the two groups were evaluated and compared.\nResults: There were 21 patients in control group, while 30 patients in observation group. The duration of mechanical ventilation, duration of delirium and the length of ICU stay in the observation group were significantly shorter than that in the control group (P<0.05). The number of lymphocytes and body weight in the observation group were significantly higher than those in the control group (P<0.05). The complication rate in the observation group was significantly lower than that in the control group (P<0.05). The time of patients reaching the nutritional target in the observation group was significantly earlier than that in the control group (P<0.05).\nConclusion: The enteral nutritional support on ICU patients with mechanical ventilation is particularly effective, which effectively reduce the occurrence of delirium and other complications, thus improving the prognosis, which is of clinical application value.

To explore the short-term effects of laparoscopic radical resection of sigmoid colon cancer with modified triangular anastomosis technique and laparoscopic-assisted small incision colon cancer reconstruction surgery. A total of 86 patients with sigmoid colon cancer who were admitted to our hospital from April 2019 to January 2021 were selected and divided into two groups using a random number table method. All patients received radical resection of sigmoid colon cancer. During the reconstruction of the digestive tract In the control group, patients underwent laparoscopic-assisted small-incision reconstruction surgery, and patients in the observation group underwent complete laparoscopic surgery with modified triangular anastomosis technique. The two groups were compared with perioperative related indicators, postoperative complications, and follow-up for 3 months. Local tumor recurrence and metastasis, abdominal wall puncture and implantation, and death occurred within. Compared with the control group, the observation group had shorter operation time, gastrointestinal reconstruction time, postoperative exhaust time, hospitalization time, and less intraoperative blood loss (P<0.05). There was no significant difference in the number of lymph node dissections between the two groups (P >0.05); the observation group had a significantly lower probability of complications (P<0.05); the two groups of patients were followed up for 3 months, and there was no local tumor recurrence, distant tumor metastasis, abdominal wall puncture implantation, and death.

Background: Breast cancer, a very heterogeneous systemic disease, is the second leading cause of death in worldwide. The specific regulatory mechanism of different subtype of breast cancer progression and metastasis was unclear. Liprin family plays an important role in the development and progression of tumors. Whereases the function of LPNA3 in BRCA (Breast Cancer) remains unknown. \nMaterials and Methods: LPNA3 expression and clinical information of BRCA were extracted from TCGA dataset. Then, expression level of LPNA3 was explored in BRCA from different angles, including clinical stage, molecular subtype, ER and PR status. Then, function enrichment analysis of LPNA3 co-expressed genes and GSEA was carried out to estimate the role of LPNA3 participate in BRCA. At last, the survival analysis was carried to evaluate the prognostic value of LPNA3 in BRCA. \nResults: LPNA3 was increased in breast cancer compare to the paracancerous tissue. Then, LPNA3 has a higher expression level in late-stage breast cancer, ER negative group, and basal subtype of BRCA. Subsequently, function enrichment analysis and GSEA (Gene Set Enrichment Analysis) indicated that LPNA3 mainly involved in translational regulation and adherens function. Survival analysis suggested patients with lower LPNA3 have a promising prognosis compared to those with higher LPNA3 expression level.\nConclusion: LPNA3 served as a marker for poor prognosis of BRCA.

Fertilizer management is an important consideration in corn production system because it is essential for the crop\'s growth and development. Moreover, another key focus for improving fertilizer use efficiency and increasing corn productivity is timing of fertilizer application at suitable crop growth stage. Therefore, a field research was conducted during 2019, at Field 15, Faculty of Agriculture, University Putra Malaysia, to quantify the effect of four fertilizer application regimes T1 (1, 3 and 4 weeks after planting-WAP), T2 (2, 4 and 6 WAP), T3 (2, 4, 6 and 8 WAP), and T4 (2, 4, 8 and 10 WAP) on growth and yield attributes of two corn varieties (GWG888 and CP888) and weed composition. The results indicated that both factors (fertilizer application regimes and varieties) significantly influenced corn growth, yield and weed composition. It was observed that T3 (application of fertilizer at 2, 4, 6 and 8 WAP) for GWG corn variety produced the highest plant height, leaf area, cob length, dry matter yield, crude protein and N, P, K content, while it decreased NDF, ADF and lignin content compared to other treatments. Meanwhile, Broadleaf weeds showed higher dominance in all fertilizer application regimes compared to grasses and sedges weed. Our findings suggest that the use of fertilizer up to 8 WAP resulted in sufficient nutrients supply for flowering and after flowering stages, which improving corn growth, yield and forage quality.

Background: The performance of the complaint management system in hospitals significantly affects the quality of services in the health system and improves client satisfaction. This study aimed to compare the patient complaint management system in hospitals of selected countries and Iran to identify the shortcomings in the Iranian complaint management system and design a model for it.\nMethods: In this study, some basic information related to the complaint management system (executive structure; executive mechanism and control mechanism) by referring to the websites of organizations related to the health system of selected countries (Australia, USA, UK, South Africa, Turkey) And Iran, as well as related and up-to-date articles were collected in Scopus, Science Direct, Web of science, Magiran, Elsevier, etc. databases and Google Scholar search engine. The required items were extracted using the Delphi method, and finally, 41 items were agreed upon by experts. In the field study, 215 relevant experts and managers in complaint management from all over Shakur answered the relevant questionnaire. Exploratory factor analysis was used to discover and confirm the model\'s dimensions with the help of EQS6 and SPSS22 software.\nFindings: The current situation of the complaint management system in Iranian hospitals creates challenges in improving the quality of services and client satisfaction. Based on experts\' opinions, factors influencing the grievance management system of countries (41 cases) were extracted. Heuristic and confirmatory factor analysis were used to examine the possible relationship between factors and their effectiveness. Finally, four structural (CFI = 1.35), Managerial (CFI = 0.33), executive (CFI=1.13) and compensatory (CFI = 0.22) factors were discovered and approved for the proposed model.\nConclusion: The patient complaints management system in Iranian hospitals can overcome the existing challenges by reviewing and formulating structural, managerial, executive, and compensatory measures, and by using the experiences of prosperous countries, and while creating coherence, improve the quality of services and Provides patient satisfaction.

The aim of this paper is to examine a new extraction system involving a mixture of the organic acids (Cyanex 272 and caprylic acid) for the extraction and separation of lanthanides(III). The extraction of lanthanides(III) from chloride-acetate and nitrate-acetate media using La(III) as an example was investigated. The mixtures of these acids possess high extraction ability and extraction capacity. The extracted species as La(OOCCH3)2A.sН2В2 are suggested based on the analysis of the extraction isotherms in the La(III) extraction from chloride-acetate and nitrate-acetate solutions with mixtures of di(2,4,4-trimethylpentyl)phosphinic acid (Cyanex 272) and caprylic acid. While using acetic-acetate aqueous solutions, extraction of La(III) reduces because of decreasing equilibrium pH of the aqueous phase in accordance with cation-exchange mechanism. The separation of lanthanides(III) can be achieved in the extraction with mixtures of Cyanex 272 and caprylic acid in hexane from acetic-acetate solutions.