Study using questionnaire on peasants and professionals followed by experimental study using available drugs on trypanosome isolates in mice conducted in Amhara region of north western Ethiopia, for assessment of malpractices and presence of multidrug resistance. From survey, malpractices of drug administration by animal owners themselves (71.7%); the use of non-conventional drug administration routes (12%), under dosing (54%) in fear of toxicity and use of other medications together with trypanocides (1.65%) were obtained in peasants. Only 20.4% of veterinary service personnel use laboratory diagnosis as aid for confirmatory diagnosis before treatment. In experimental studies, the drugs tested for sensitivity observed with relapses duration of 5.8�0.96 days with 70mg/kg Diminazine aceturate; 14.2�1.99days with 10mg/kg Isometamidium chloride and 4.6�3.75 days with 10mg/kg Homidium chloride. Relapse duration was longer with isometamidium (p<0.001) than others. Both single drug therapy as well as use of sanative pairs unable to clear tested groups. However, 60 % of mice in 70mg/kg diminazene aceturate followed by isometamidium chloride result in complete clearance. Longer relapse duration observed in sanative pair use (P<0.001) than single therapy. Malpractices and existence of trypanosome isolates resistant to sanative combination was demonstrated. Regulatory compliance and community mobilization for wise use of available trypanocides is recommended.
Many real-world classification tasks in agriculture are faced with the problem of imbalanced data due to the various data distribution. Classic machine learning algorithms perform poorly on the imbalanced classification, usually ignoring the samples in minority class to achieve a good overall accuracy. In order to solve this problem, we proposed an improved oversampling approach, called H-SMOTE, to rebalance the original imbalanced data in a stable and reasonable way. Experiments were carried out on 12 datasets from the public Abalone database, covering a wide range of imbalance rate from 3.8 to 16.4. Two typical classifiers SVM (support vector machine) and Random Forest were selected to testify the performance and generalization of H-SMOTE. Moreover, the typical oversampling algorithm SMOTE was adopted as the baseline of comparison. Extensive experimental results show that the proposed H-SMOTE outperforms the SMOTE in terms of all the evaluation indicators, including accuracy, recall, F-measure, G-mean and AUC. Furthermore, compared with the SMOTE, the distributions of datasets oversampled by H-SMOTE are more uniform and stable. Thus, this study provides an improved oversampling method aiming at the imbalanced classification.
In this paper tested the single stage-single-switch center-tapped AC-DC rectifier as a PFC for low power applications. This proposed topology has some advantages such as lighting systems, SMPS, charger cable and low amount of load power applications. This proposed topology is almost utilized laboratory and industries. This has minimum cost for implementation because of minimum amount of component requirements and its switches are consumes low amount of power, it is achieved high power factor that is almost unity state in this proposed system, and it has high efficiency and operating speed is high. Furthermore this AC-DC converter is self-controlled with the closed-loop system of Proportional Integral Derivative (PID) and Proportional Integral (PI) controller that is commonly used closed loop controller in research field. In this topology utilized to simulink test, after the center tapped transformer utilized for step down process. This topology of experiment verified and tested by Mat lab Simulation with waveform results that closed loop system expressed in accurate values of waveform in this paper and prototype is tested and verified done by using suitable laboratory kits for low power variable load such as motor and LED and resistive low power loads have been tested and verified.
In this study, it was aimed to investigate the feasibility of new generation Sn/Sb/Ni-Ti anodes in electrochemical oxidation of wastewater containing ampicillin (AMP) antibiotic. Two different type of salt were used and evaluated as electrolyte: sodium chloride (NaCl) and potassium chloride (KCl). However, the removal efficiencies were found higher in the presence of KCl. With KCl, complete removal of chemical oxygen demand (COD) and AMP were occured after 60 and 5 min; while it was necessary using NaCl after 90 and 5 min, respectively. The optimum conditions were: 0,75 g L-1 KCl, pH 8 and 50 mA cm-2 current density.
The intensity of alcohol metabolism in a human body has crucial influence on the purine metabolism, which reflects in serum urate values. We found increased serum urate values in 23.5% of alcohol dependents. For the first time we published the serum urate values in women addicted to alcohol. We found statistic significant lower serum urate values in alcohol dependent men with withdrawal state. The urate value at hospital reception is anyway beneficial indirect information about patients metabolic state.